Publications by Shenfeng Qiu

ssbm_4_samples_integrated

16.08.2023

Edited by Shenfeng Qiu 07232023 CAN RUN ALL BLOCK BY BLOCK BEAUTIFULLY, INCLUDING MONOCLE3, AZIMUTH MAPPING AND SHINYCELL VISUALIZATION with reference to: https://satijalab.org/seurat/articles/integration_introduction.html Import Group samples Quality Control Plot Data Joint filtering effects: After subseting, I only keep those genes expresse...

2684 sym 53 img

Anndata file manipulation

15.08.2023

Download Example Tabula Sapiens Anndata Object and Manipulation !wget https://figshare.com/ndownloader/files/34701991 # not working with Anaconda terminal, has to be wsl terminal The following block will download the TS_lung.h5ad file into current directory import requests from zipfile import ZipFile from io import BytesIO # Downloading the fi...

379 sym Python (10038 sym/49 pcs) 5 tbl

Simple Volcano plot for seurat .csv file

07.08.2023

Reference: https://bioconductor.org/packages/devel/bioc/vignettes/EnhancedVolcano/inst/doc/EnhancedVolcano.html#download-the-package-from-bioconductor # use the next block for plotting # Load required libraries library(ggplot2) library(dplyr) ## ## Attaching package: 'dplyr' ## The following objects are masked from 'package:stats': ## ## ...

389 sym R (9480 sym/19 pcs) 10 img

human bone marrow sample

25.07.2023

#load seurat package and dependencies library(dplyr) library(Seurat) library(patchwork) library(cowplot) library(ggplot2) library(rstatix) library(RColorBrewer) setwd("D:/Bioinformatics Projects/shalini_bm_noe15") load NoE15 dataset # read the NoE15 sample NoE15.data <- Read10X(data.dir = "NoE15/outs/filtered_feature_bc_matrix/") dim(NoE1...

1061 sym R (28293 sym/149 pcs) 22 img

ss_one_bone_marrow_E15

24.07.2023

#load seurat package and dependencies library(dplyr) library(Seurat) ## Warning: package 'Seurat' was built under R version 4.2.2 library(patchwork) library(cowplot) library(ggplot2) ## Warning: package 'ggplot2' was built under R version 4.2.1 library(rstatix) library(RColorBrewer) setwd("D:/Bioinformatics Projects/shalini_bm") load E15 datas...

1067 sym R (28008 sym/157 pcs) 22 img

bulk RNAseq analysis - mouse brain tissue

10.04.2023

SQ NOTE: use this to process the mouse bulk RNAseq data, three FAD vs three Ctrl samples. can run all, no problem. By default, the ctrl (ref) samples will be on the left side of the csv file, and fad sample on the right side of csv file. if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::insta...

389 sym R (18152 sym/94 pcs) 3 img

DESeq bulk analysis online tutorial

09.04.2023

https://genviz.org/module-04-expression/0004/02/01/DifferentialExpression/ SQ NOTE: can run ALL library(DESeq2) ## Loading required package: S4Vectors ## Loading required package: stats4 ## Loading required package: BiocGenerics ## ## Attaching package: 'BiocGenerics' ## The following objects are masked from 'package:stats': ## ## IQR, ma...

216 sym R (49872 sym/107 pcs) 9 img

Another DESeq2 tutorial from counting matrix

09.04.2023

Source https://lashlock.github.io/compbio/R_presentation.html SQ NOTE: can run ALL library(DESeq2) ## Loading required package: S4Vectors ## Loading required package: stats4 ## Loading required package: BiocGenerics ## ## Attaching package: 'BiocGenerics' ## The following objects are masked from 'package:stats': ## ## IQR, mad, sd, var, xt...

507 sym R (10619 sym/55 pcs) 3 img

bulk RNAseq analysis

08.04.2023

SQ NOTE: All block can run library(DESeq2) library(ggplot2) library(ComplexHeatmap) library("org.Hs.eg.db") ls ## HS_STAR_dir ## Homo_sapiens.GRCh38.109.gtf ## Homo_sapiens.GRCh38.dna_sm.primary_assembly.fa ## Sanbomics_RNAseq_video6.ipynb ## bams ## count.out ## count.out.summary ## count_table.csv ## deseq_results.csv ## deseq_workspa...

126 sym R (57750 sym/64 pcs) 4 img

Signac_PMBC_10K

19.03.2023

For this tutorial, we will be analyzing a single-cell ATAC-seq dataset of human peripheral blood mononuclear cells (PBMCs) provided by 10x Genomics. The following files are used in this vignette, all available through the 10x Genomics website: The Raw data The Metadata The fragments file The fragments file index View data download code To...

17043 sym R (17993 sym/48 pcs) 9 img