Publications by Rebecca Kerrigan
Follicle stimulating hormone html
Image from: Decatur, W. and Harel, M. (2014).Glycosylated FSH complex with acetylamino-deoxy-pyranose and sulfate binding to the leucine-rich domain of Follicle Stimulating Hormone Receptor. [image] Available at: https://proteopedia.org/wiki/index.php/Human_Follicle-Stimulating_Hormone_Complexed_with_its_Receptor [Accessed 7 Mar. 2020]. Follicl...
1657 sym 1 img
P-cadherin
Image from: Weizmann Institute of Science., 2020. Crystal structure of human P-Cadherin EC1-EC2 in closed conformation. Israel: Weizmann Institute of Science. P-cadherin is a cell-cell adhesion molecule that plays a role in cancer development (Vieira A.F. and Paredes, 2015). It produces stable cell junctions by working with βctn and p120ctn m...
980 sym 1 img
Phospholipase C Beta (PLCβ)
Image from: Proteopedia (2020). An animated image of Phospholipase C Beta illustrating its one chain structure. [image] Available at: https://proteopedia.org/wiki/index.php/2zkm [Accessed 8 Mar. 2020]. Phospholipase C is an enzyme responsible for the hydrolisation of phosphatidylinsoditol 4,5-bisphospate (Liao and Carpenter, 2010). Phospholipa...
1357 sym 1 img
c-Fos
Image depicting the 4 possible c-Fos/c-Jun dimers. From: VÁMOSI, G., BAUDENDISTEL, N., VON DER LIETH, C., SZALÓKI, N., MOCSÁR, G., MÜLLER, G., BRÁZDA, P., WALDECK, W., DAMJANOVICH, S., LANGOWSKI, J. & TÓTH, K.Conformation of the c-Fos/c-Jun Complex In Vivo: A Combined FRET, FCCS, and MD-Modeling Study., 2008.Biophysical Journal. Available f...
1241 sym 1 img
Goserelin
The chemical structure of goserelin from: National Center for Biotechnology Information. PubChem Database. Goserelin, CID=5311128, https://pubchem.ncbi.nlm.nih.gov/compound/Goserelin (accessed on Mar. 8, 2020). Gorerelin or Zoladex is a man-made form of luteinizing hormone releasing hormone so its mechanism of action is to interact with gonadot...
990 sym
Leuprolide Acetate
The chemical structure of leuprolide acetate from: National Center for Biotechnology Information. PubChem Database. 53714-56-0, Source=KEGG, SID=96024803, https://pubchem.ncbi.nlm.nih.gov/substance/96024803 (accessed on Mar. 8, 2020). Currently leuprolide is used to treat prostate cancers but research is being done into treatment for other canc...
1448 sym
c-Jun
Image from: Weizmann Institute of Science., 2019. NMR STUDY OF C-JUN HOMODIMER. Isreal: Weizmann Institute of Science. It depicts a 3D animation of human c-Jun c-Jun is a transcription factor responsible for signal transduction in several signalling pathways, through phosphorylation (Dunn, Wiltshire, MacLaren & Gillespie, 2002). It is selectiv...
1034 sym 1 img
Phospholipase D
Image from: LI, J. X., YU, F. & ZHANG, P., 2020. Crystal structure of plant Phospholipase D alpha comlex with phosphatidic acid. Israel: Weizmann Institute of Science. Phospholipase D promotes the formation of phosphatidic acid by hydrolysing the phosphodiester bond in glycerophospholipids (McDermott, Wakelam and Morris, 2004). There are two i...
864 sym 1 img
Elk-1
Image from: Besnard, A., Galan-Rodriguez, B., Vanhoutte, P. and Caboche, J. (2011). Elk-1 a Transcription Factor with Multiple Facets in the Brain. Frontiers in Neuroscience, [online] 5. Available at: https://www.frontiersin.org/articles/10.3389/fnins.2011.00035/full [Accessed 8 Mar. 2020]. Elk-1 is a transcription factor that, using the serum...
1152 sym 1 img
Phosphatidylinositol 4,5-bisphosphate (PIP2)
Image from: RAJALA, R.V.S. & ANDERSON, R.E., 2010. Focus on Molecules: Phosphatidylinositol-4,5-bisphosphate (PIP 2). Experimental Eye Research. 91(3), pp.324-325. Available from: 10.1016/j.exer.2010.05.001. Phosphatidylinositol 4,5-bisphosphate is an important secondary messenger molecule located in the plasma membrane of the cell (Rajala and ...
986 sym 1 img